Microwave-assisted synthesis of some 1,2,4-triazol-5-one derivatives
HETEROATOM CHEMISTRY, cilt.19, sa.1, ss.38-42, 2008 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 19 Sayı: 1
- Basım Tarihi: 2008
- Doi Numarası: 10.1002/hc.20381
- Dergi Adı: HETEROATOM CHEMISTRY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.38-42
- Recep Tayyip Erdoğan Üniversitesi Adresli: Evet
Özet
A series of 3-alkyl(aryl)-4-(p-hydroxy -phenyl)-4,5-dihydro-1H-1,2,4-triazol-5-ones 2 were obtained from the reaction of alkyl (aryl) ester ethoxycarbonyl hydrazones I with p-hydroxy aniline. The reaction of I with 1,4-diamino benzene (1:1) to afford 3-alkyl(aryl)-4- (p-aminophenyl)-4,5-dihydro-1H-1,2,4-triazol-5-ones 3. The reaction of 3 with benzaldehyde gave 3-alkyl(aryl)-4-(4'-benzilidenamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones 4. All of the above reactions occurred under microwave heating and conventional methods. Their structures were confirmed by H-1 NMR, C-13 NMR, IR, and elemental analyses. (C) 2008 Wiley Periodicals, Inc.