The independent relationship between systemic inflammation and fragmented QRS complexes in patients with stable angina pectoris

Cetin M., KOCAMAN S. A., CANGA A., DURAKOĞLUGİL M. E., ERDOĞAN T., ŞATIROĞLU Ö., ...More

KARDIOLOGIA POLSKA, vol.70, no.7, pp.668-676, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 70 Issue: 7
  • Publication Date: 2012
  • Journal Name: KARDIOLOGIA POLSKA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.668-676
  • Keywords: fragmented QRS, fQRS, coronary artery disease, cardiovascular risk, inflammation, left ventricular dysfunction, coronary atherosclerotic burden, C-REACTIVE PROTEIN, CORONARY-ARTERY-DISEASE, BUNDLE-BRANCH BLOCK, MYOCARDIAL-INFARCTION, DILATED CARDIOMYOPATHY, CARDIOVASCULAR-DISEASE, CARDIAC FIBROSIS, ANATOMIC BASIS, HEART-FAILURE, QTC INTERVAL
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

Background: QRS complex fragmentations can frequently be seen on routine ECG with narrow or wide QRS complex. Fragmented QRS complexes (fQRS) are defined as various RSR' patterns (>= 1 R' or notching of S wave or R wave) in two contiguous leads corresponding to a major coronary artery territory. In previous studies, fQRS has been associated with increased morbidity and mortality, sudden cardiac death and recurrent cardiovascular events. The causative relationship between fQRS and cardiac fibrosis has been shown, but it has not been extensively studied whether there are different mechanisms for the development of fQRS.