Efficient microwave assisted synthesis of some new benzimidazoles containing the mebendazole nucleus

Mentese E.

JOURNAL OF CHEMICAL RESEARCH, no.3, pp.168-170, 2013 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: Issue: 3
  • Publication Date: 2013
  • Doi Number: 10.3184/174751913x13603595770952
  • Journal Name: JOURNAL OF CHEMICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.168-170
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

A simple and practical method has been developed for the synthesis of benzimidazoles containing the biological active mebendazole nucleus. Iminoester hydrochlorides of phenylacetic acids were used as intermediates in the reaction with 3,4-diaminobenzophenone under microwave irradiation leading to the products in good yields and in short reaction times.