Prevalence of integrons and a new dfrA17 variant in Gram-negative bacilli which cause community-acquired infections


Sandalli C., BURUK C. K. , SANCAKTAR M., ÖZGÜMÜŞ O. B.

MICROBIOLOGY AND IMMUNOLOGY, vol.54, no.3, pp.164-169, 2010 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 54 Issue: 3
  • Publication Date: 2010
  • Doi Number: 10.1111/j.1348-0421.2010.00197.x
  • Title of Journal : MICROBIOLOGY AND IMMUNOLOGY
  • Page Numbers: pp.164-169

Abstract

A hundred and eleven Gram-negative bacilli from community-acquired infections were characterized by antimicrobial susceptibility testing, screened for class 1 and 2 integrons, and statistically evaluated for the association between antibiotic profile and the presence of integrons. The frequency with which integrons were harbored was 28.8%. Three E. coli strains contained a dfrA17 variant inserted in a class 1 integron. Results of PFGE indicated that some E. coli strains carrying integrons were clonally related. Carriage of gene cassettes was significantly associated with resistance to certain antibiotics (P < 0.05).