Glutamine Supplemented Parenteral Nutrition to PreventVentilator-Associated Pneumonia in the Intensive Care Unit

Aydogmus M. T., Tomak Y., Tekin M., Kati I., Huseyinoglu U.

BALKAN MEDICAL JOURNAL, vol.29, no.4, pp.414-418, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 4
  • Publication Date: 2012
  • Doi Number: 10.5152/balkanmedj.2012.043
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.414-418
  • Recep Tayyip Erdoğan University Affiliated: Yes


Objective: Ventilator-associated pneumonia (VAP) is a form of nosocomial pneumonia that increases patient morbidity and mortality, length of-hospital stay, and healthcare costs. Glutamine preserves the intestinal mucosal structure, increases immune function, and reduces harmful changes in gut permeability in patients receiving total parenteral nutrition (TPN). We hypothesized that TPN supplemented by glutamine might prevent the development of VAP in patients on mechanical ventilator support in the intensive care unit (ICU).