Glutamine Supplemented Parenteral Nutrition to PreventVentilator-Associated Pneumonia in the Intensive Care Unit

Aydogmus M. T. , Tomak Y., Tekin M., Kati I., Huseyinoglu U.

BALKAN MEDICAL JOURNAL, cilt.29, sa.4, ss.414-418, 2012 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 29 Konu: 4
  • Basım Tarihi: 2012
  • Doi Numarası: 10.5152/balkanmedj.2012.043
  • Sayfa Sayıları: ss.414-418


Objective: Ventilator-associated pneumonia (VAP) is a form of nosocomial pneumonia that increases patient morbidity and mortality, length of-hospital stay, and healthcare costs. Glutamine preserves the intestinal mucosal structure, increases immune function, and reduces harmful changes in gut permeability in patients receiving total parenteral nutrition (TPN). We hypothesized that TPN supplemented by glutamine might prevent the development of VAP in patients on mechanical ventilator support in the intensive care unit (ICU).