Inhibiting renin angiotensin system in rate limiting step by aliskiren as a new approach for preventing indomethacin induced gastric ulcers


HALICI Z., Polat B., ÇADIRCI E., Topcu A. , Karakus E., KÖSE D., ...More

CHEMICO-BIOLOGICAL INTERACTIONS, vol.258, pp.266-275, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 258
  • Publication Date: 2016
  • Doi Number: 10.1016/j.cbi.2016.09.011
  • Title of Journal : CHEMICO-BIOLOGICAL INTERACTIONS
  • Page Numbers: pp.266-275

Abstract

Purpose: Previously blocking the renin angiotensin system (RAAS) has been effective in the prevention of gastric damage. Therefore, the aim of this study was to investigate the effects of aliskiren, and thus, direct renin blockage, in indomethacin-induced gastric damage model.