Medical ozone therapy reduces oxidative stress and testicular damage in an experimental model of testicular torsion in rats

TUSAT M., MENTEŞE A., DEMİR S., ALVER A., İMAMOĞLU M.

INTERNATIONAL BRAZ J UROL, vol.43, no.6, pp.1160-1166, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 6
  • Publication Date: 2017
  • Doi Number: 10.1590/s1677-5538.ibju.2016.0546
  • Journal Name: INTERNATIONAL BRAZ J UROL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1160-1166
  • Recep Tayyip Erdoğan University Affiliated: No

Abstract

Objective: Testicular torsion (TT) refers to rotation of the testis and twisting of the spermatic cord. TT results in ischemia-reperfusion (I/R) injury involving increased oxidative stress, inflammation and apoptosis, and can even lead to infertility. The aim of this study was to investigate the effect of ozone therapy on testicular damage due to I/R injury in an experimental torsion model.