Increased circulating soluble CD40 levels in patients with slow coronary flow phenomenon: an observational study
ANADOLU KARDIYOLOJI DERGISI-THE ANATOLIAN JOURNAL OF CARDIOLOGY, vol.13, no.1, pp.39-44, 2013 (SCI-Expanded, Scopus, TRDizin)
- Publication Type: Article / Article
- Volume: 13 Issue: 1
- Publication Date: 2013
- Doi Number: 10.5152/akd.2013.005
- Journal Name: ANADOLU KARDIYOLOJI DERGISI-THE ANATOLIAN JOURNAL OF CARDIOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Page Numbers: pp.39-44
- Keywords: Slow coronary flow, soluble CD40, C-reactive protein, coronary angiography, regression analysis, HUMAN VASCULAR CELLS, ENDOTHELIAL FUNCTION, OXIDATIVE STRESS, ANGINA-PECTORIS, HUMAN MONOCYTES, ARTERY FLOW, SYNDROME-X, EXPRESSION, LIGAND, ATHEROSCLEROSIS
- Recep Tayyip Erdoğan University Affiliated: Yes
Abstract
Objective: Slow coronary flow (SCF) is an angiographic finding characterized with delayed opacification of epicardial coronary arteries without obstructive coronary disease. CD40/CD40 ligand (CD40L) signaling seems closely related to atherosclerosis due to increased inflammation and prothrombotic state. We investigated whether soluble CD40 (sCD40), an indirect marker of CD40/CD40L dyad, is related to SCF.