Microwave-Assisted Synthesis of Benzimidazoles and Their Derivatives From 1994 to 2016-A Review


KAHVECİ B., Mentese E.

CURRENT MICROWAVE CHEMISTRY, vol.4, no.1, pp.73-101, 2017 (ESCI) identifier

Abstract

Background: The use of microwave irradiation is an important development for the synthesis of benzimidazoles in the 21st century, and in recent years, microwave-assisted heterocyclic synthesis has gained significant attention in modern drug discovery studies. Benzimidazoles are an important group in the field of medicinal chemistry because of a wide range of biological activities. This review article provides a collection of studies on the synthesis of benzimidazole derivatives by microwave techniques over a twenty-one years period for an alternative to conventional heating.