Research Information System
7.EACID2015, Tiflis, Georgia, 30 September - 03 October 2015, pp.267-268
OBJECTIVE: We aimed to evaluate the factors affecting mortality in patients treated in ICUs and to determine the measures to be
taken to reduce the mortality rate.
METHODS: This retrospective cohort study was performed with 810 ICU patients of 66.2±15.9 ages in 2013. Age, sex, diagnosis
for admission to ICU and underlying disease, APACHE II score, Charlson co-morbidity index results, duration of hospitalization,
infections, treatments, and invasive procedures were recorded. All data were obtained by examining files of patients, nurses’
observations, the infection control committee records, pharmacy data, treatment, surgical notes, and laboratory reports.
RESULTS: The average hospitalization was 17.3±20.6 days. Charlson co-morbidity index of the patients was 3.1±1.8, and APACHE
II score was 19.7±3.0. 497 of the patients (61.4%) died and the mortality rate was found to be 23.7 per 1000 patient days. APACHE
II score, the presence of nosocomial infections, and cerebrovascular disease were independent risk factors affecting mortality in
multivariable analysis. Predicted mortality rate by APACHE II score was determined as 45.6%. Standardized mortality rate was
1.35. 566 patients were hospitalized longer than 48 hours and 309 hospital infections developed in 205 of these patients. Hospital
infection rate was 25.4 per 1000 patient day (Table 1).
CONCLUSION: High APACHE II score, Charlson co-morbidity index and nosocomial infections are the most important factors
affecting mortality. The development of infection should be prevented to reduce the mortality rate and appropriate therapy should
be started at once in the presence of an infection.
KEY WORDS: Intensive care, mortality, infection.