Contribution of myeloperoxidase and inducible nitric oxide synthase to pathogenesis of psoriasis

DILEK N., DILEK A. R., TASKIN Y., ERKINURESIN T., YALCIN O., Saral Y.

POSTEPY DERMATOLOGII I ALERGOLOGII, cilt.33, sa.6, ss.435-439, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 6
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5114/ada.2016.63882
  • Dergi Adı: POSTEPY DERMATOLOGII I ALERGOLOGII
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.435-439
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

Introduction: Histological changes of psoriasis include invasion of neutrophils into the epidermis and formation of Munro abscesses in the epidermis. Neutrophils are the predominant white blood cells in circulation when stimulated; they discharge the abundant myeloperoxidase (MPO) enzyme that uses hydrogen peroxide to oxidize chloride for killing ingested bacteria.