Role of diffusion-weighted imaging and dynamic contrast enhanced magnetic resonance imaging in the diagnosis of early sacroiliitis in seronegative spondyloarthropathies, correlation with levels of acute phase reactants


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Aydin Aksu S., GÜNDOĞDU H.

MARMARA MEDICAL JOURNAL, vol.35, no.1, pp.79-87, 2022 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 1
  • Publication Date: 2022
  • Doi Number: 10.5472/marumj.1061146
  • Title of Journal : MARMARA MEDICAL JOURNAL
  • Page Numbers: pp.79-87
  • Keywords: Seronegative spondyloarthropathy, Early sacroiliitis, Dynamic contrast enhanced magnetic resonance imaging, Diffusion-weighted magnetic resonance imaging, Acute phase reactants, SPONDYLARTHROPATHY, RADIOGRAPHY, JOINTS, STAGE, DWI, MRI

Abstract

Objective: Seronegative spondyloarthropathy (SpA) is a destructive disease. Early diagnosis is crucial to prevent morbidity. Magnetic resonance imaging (MRI) is the only imaging modality that can show early sacroiliitis. We aimed to investigate the utility of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) and diffusion-weighted imaging (DWI) in the detection, quantification and staging of early/acute SpA. We also investigated the relationship between contrast enhancement properties and apparent diffusion coefficient (ADC) values with laboratory parameters for inflammation such as ESR and CRP measurments.