Histological Investigation of the Effects of Tenoxicam on Pulmonary Complications of Pneumoperitoneum - Tenoxicam Reduces Lung Injuries Caused by Pneumoperitoneum


Gezer S., Karapolat S., YILDIRIM Ü., TÜRÜT H. , Erbas M., ÖZAYDIN İ.

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, vol.20, no.4, pp.503-507, 2011 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 4
  • Publication Date: 2011
  • Title of Journal : ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE
  • Page Numbers: pp.503-507

Abstract

Objectives. Pneumoperitoneum increases intra-abdominal pressure and generates oxidative stress, which mediates tissue injury. One of the causes of oxidative stress production is an inflammatory reaction. Taking this into consideration, the current animal study was designed, using tenoxicam before a laparoscopy procedure in order to ascertain whether tenoxicam can prevent lung injury caused by pneumoperitoenum.