THE EFFECTIVENESS OF ELECTRO-ACUPUNCTURE IN OVARIAN ISCHEMIA REPERFUSION INJURY

Keskin S., Keskin D. D., Degermenci M., Hanci H., Karabekir N. G., Atak M., ...Daha Fazla

ACUPUNCTURE & ELECTRO-THERAPEUTICS RESEARCH, cilt.47, sa.1, ss.47-58, 2021 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 1
  • Basım Tarihi: 2021
  • Doi Numarası: 10.3727/036012921x16264625521781
  • Dergi Adı: ACUPUNCTURE & ELECTRO-THERAPEUTICS RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE
  • Sayfa Sayıları: ss.47-58
  • Anahtar Kelimeler: Ovarian torsion, Ovarian ischemia/reperfusion injury, Electro-acupuncture, AMH, Ovarian reserve, Complementary and traditional medicine, BLOOD-FLOW, ABDOMINAL ELECTROACUPUNCTURE, INFERTILE WOMEN, RAT MODEL, ACUPUNCTURE, STIMULATION, MECHANISMS, FREQUENCY, TORSION, POINT
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

Electro-acupuncture is widely used in gynecology. Adnexal torsion is an important threat to ovarian reserves in women of reproductive age. This is the first study to investigate whether electro-acupuncture is beneficial in protecting ovarian reserves in case of adnexal torsion resulting in reperfusion injury. Thirty-two female Wistar Albino rats were randomized into four groups: the first group-sham operation, the second group-torsion/detorsion model, the third group-pre-acupunture + torsion/detorsion + post-acupuncture, and the fourth group-torsion/detorsion + post-acupuncture. The acupoints used were CV4 and bilateral SP6, Ex-CA1, Kid3, and ST36. In the third group, the acupoints were needled for two weeks before torsion, continuing for a further two weeks after torsion. In the fourth group, needling began after torsion and was maintained for two weeks. Both histological and biochemical parameters indicating ovarian reserves showed that electro-acupuncture applied to the above points exhibited an ameliorating effect on ovaries injured during ischemia/reperfusion. Electro-acupuncture may be capable of protecting against and preventing ischemia/reperfusion injury in case of ovarian torsion.