Pseudoactinomycotic radiate granules (PAMRAGs) in the extensor tendon of hand
Journal of the College of Physicians and Surgeons Pakistan, vol.31, no.12, pp.1503-1505, 2021 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 31 Issue: 12
- Publication Date: 2021
- Doi Number: 10.29271/jcpsp.2021.12.1503
- Journal Name: Journal of the College of Physicians and Surgeons Pakistan
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
- Page Numbers: pp.1503-1505
- Keywords: Actinomyces, Extensor tendon, Hand, Pseudoactinomycotic radiate granules (PAMRAGs)
- Open Archive Collection: AVESIS Open Access Collection
- Recep Tayyip Erdoğan University Affiliated: Yes
Abstract
Pseudoactinomycotic radiate granules (PAMRAGs) are most frequently observed in female genitalia. Morphologically, these closely resemble the actual actinomycotic granules. Actinomyces are infectious organisms that require treatment; whereas, PAMRAGs do not require a specific treatment since they are not infectious. Here, we describe a previously unreported case of these granules in the hand. A 56-year woman was admitted with soft mass on the dorsal aspect of her right hand. Peroperatively, lesion was detected in the extensor digitorum communis. Histopathological examination revealed an appearance that resembled actinomyces. Periodic acid-Schiff (PAS) staining was not positive for actinomyces. Hematoxylin-eosin (HE) staining showed radially arranged refractile granules with thick, irregular club-like eosinophilic character without a central core. Thus, actinomycosis was ruled out and a diagnosis of PAMRAGs was made. Differentiating PAMRAGs from actual actinomycotic infections is crucial for the treatment. Pathologists should be familiar with the presence and appearance of PAMRAGs to avoid misdiagnosis of actinomycosis and prevent unnecessary antibiotic use.