Increased Serum Bilirubin Level is Related to Good Collateral Development in Patients with Chronic Total Coronary Occlusion

Erdogan T., Cicek Y., KOCAMAN S. A., CANGA A., Cetin M., Durakoglugil E., ...More

INTERNAL MEDICINE, vol.51, no.3, pp.249-255, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 51 Issue: 3
  • Publication Date: 2012
  • Doi Number: 10.2169/internalmedicine.51.6417
  • Journal Name: INTERNAL MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.249-255
  • Keywords: coronary artery disease, collateral development, bilirubin, chronic total occlusion, glucose, antioxidant, LOW-DENSITY-LIPOPROTEIN, ISCHEMIC-HEART-DISEASE, ASYMMETRIC DIMETHYLARGININE, ENDOTHELIAL DYSFUNCTION, RISK, ASSOCIATION, ANTIOXIDANT, FLOW, ATHEROSCLEROSIS, BILIVERDIN
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

Objective Bilirubin is a bile pigment with potent anti-oxidant properties; in previous studies it has been reported to be negatively associated with coronary artery disease (CAD). Although elevated serum bilirubin concentrations may protect against endothelial dysfunction, it is not clear whether higher serum bilirubin levels (SBLs) in physiological ranges may work in favor of good collateral development in patients with chronic total coronary occlusion (CTO).