Increased Serum Bilirubin Level is Related to Good Collateral Development in Patients with Chronic Total Coronary Occlusion


Erdogan T. , Cicek Y. , KOCAMAN S. A. , CANGA A., Cetin M. , Durakoglugil E., ...More

INTERNAL MEDICINE, vol.51, no.3, pp.249-255, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 51 Issue: 3
  • Publication Date: 2012
  • Doi Number: 10.2169/internalmedicine.51.6417
  • Title of Journal : INTERNAL MEDICINE
  • Page Numbers: pp.249-255
  • Keywords: coronary artery disease, collateral development, bilirubin, chronic total occlusion, glucose, antioxidant, LOW-DENSITY-LIPOPROTEIN, ISCHEMIC-HEART-DISEASE, ASYMMETRIC DIMETHYLARGININE, ENDOTHELIAL DYSFUNCTION, RISK, ASSOCIATION, ANTIOXIDANT, FLOW, ATHEROSCLEROSIS, BILIVERDIN

Abstract

Objective Bilirubin is a bile pigment with potent anti-oxidant properties; in previous studies it has been reported to be negatively associated with coronary artery disease (CAD). Although elevated serum bilirubin concentrations may protect against endothelial dysfunction, it is not clear whether higher serum bilirubin levels (SBLs) in physiological ranges may work in favor of good collateral development in patients with chronic total coronary occlusion (CTO).