Rationalization of the Irrational Neuropathologic Basis of Hypothyroidism-Olfaction Disorders Paradox: Experimental Study

Aydin N., Ramazanoglu L., Onen M. R., Yilmaz I., AYDIN M. D., Altinkaynak K., ...Daha Fazla

WORLD NEUROSURGERY, cilt.107, ss.400-408, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 107
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1016/j.wneu.2017.07.180
  • Dergi Adı: WORLD NEUROSURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.400-408
  • Anahtar Kelimeler: Hypothyroidism, Olfaction disorders, Olfactory bulbectomy, Vagal complex, SUBARACHNOID HEMORRHAGE, HEAD TRAUMA, SKULL BASE, DYSFUNCTION, DISEASE, SMELL, ABNORMALITIES, HORMONE, NERVE, RAT
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

OBJECTIVE: Hypothyroidism is defined as an underactive thyroid gland and one of the reasons for inadequate stimulation of thyroid is dysfunction of the hormone regulating brain centers. Olfaction disorders have been considered as a problem in hypothyroidism. It has been hypothesized that olfaction disorders reduce olfactory stimulation and diminished olfactory stimulus may trigger hypothyroidism. In this study, an examination was made of the thyroid hormone levels, histologic features of thyroid glands, and vagal nerve network degradation in an experimental animal model of olfactory bulbectomy (OBX).