Rationalization of the Irrational Neuropathologic Basis of Hypothyroidism-Olfaction Disorders Paradox: Experimental Study


Aydin N., Ramazanoglu L., Onen M. R. , Yilmaz I., AYDIN M. D. , Altinkaynak K., ...Daha Fazla

WORLD NEUROSURGERY, cilt.107, ss.400-408, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 107
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1016/j.wneu.2017.07.180
  • Dergi Adı: WORLD NEUROSURGERY
  • Sayfa Sayıları: ss.400-408

Özet

OBJECTIVE: Hypothyroidism is defined as an underactive thyroid gland and one of the reasons for inadequate stimulation of thyroid is dysfunction of the hormone regulating brain centers. Olfaction disorders have been considered as a problem in hypothyroidism. It has been hypothesized that olfaction disorders reduce olfactory stimulation and diminished olfactory stimulus may trigger hypothyroidism. In this study, an examination was made of the thyroid hormone levels, histologic features of thyroid glands, and vagal nerve network degradation in an experimental animal model of olfactory bulbectomy (OBX).