Examination of the Effects of Thiamine and Thiamine Pyrophosphate on Doxorubicin-Induced Experimental Cardiotoxicity

Polat, B.; Suleyman, Halis; Sener, E.; Akcay, F.

doi:10.1177/1074248414552901

Examination of the Effects of Thiamine and Thiamine Pyrophosphate on Doxorubicin-Induced Experimental Cardiotoxicity

Atıf İçin Kopyala

Polat B., Suleyman H., Sener E., Akcay F.

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS, cilt.20, sa.2, ss.221-229, 2015 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 20 Sayı: 2
Basım Tarihi: 2015
Doi Numarası: 10.1177/1074248414552901
Dergi Adı: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.221-229
Recep Tayyip Erdoğan Üniversitesi Adresli: Hayır

Özet

Background and Purpose: To investigate the effect of thiamine and thiamine pyrophosphate on doxorubicin-induced cardiotoxicity biochemically and histopathologically and to examine whether doxorubicin cardiotoxicity is related to the conversion of thiamine into thiamine pyrophosphate and inhibition of thiamine pyrophosphokinase (TPK) enzyme.