A COMPARATIVE INVESTIGATION OF THE NEPHROTOXIC EFFECTS OF VARIOUS ANTIHYPERTENSIVE DRUGS IN RATS: BIOCHEMICAL AND HISTOPATHOLOGICAL ANALYSIS
ACTA MEDICA MEDITERRANEA, cilt.30, sa.2, ss.515-521, 2014 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 30 Sayı: 2
- Basım Tarihi: 2014
- Dergi Adı: ACTA MEDICA MEDITERRANEA
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.515-521
- Recep Tayyip Erdoğan Üniversitesi Adresli: Evet
Özet
Aims: Hypertension is known to cause potentially fatal kidney damage. However, it is unclear whether long-term use of antihypertensive drugs establishes any toxic effect on the kidney. This study investigate whether clonidine, methyldopa, rilmenidine, amlodipine and ramipril establish nephrotoxic effects in rats.