A COMPARATIVE INVESTIGATION OF THE NEPHROTOXIC EFFECTS OF VARIOUS ANTIHYPERTENSIVE DRUGS IN RATS: BIOCHEMICAL AND HISTOPATHOLOGICAL ANALYSIS

Malkoc I., ALTUNKAYNAK K., TURAN M. I., Gursan N., HACIMÜFTÜOĞLU A., Akcay F., ...Daha Fazla

ACTA MEDICA MEDITERRANEA, cilt.30, sa.2, ss.515-521, 2014 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 2
  • Basım Tarihi: 2014
  • Dergi Adı: ACTA MEDICA MEDITERRANEA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.515-521
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

Aims: Hypertension is known to cause potentially fatal kidney damage. However, it is unclear whether long-term use of antihypertensive drugs establishes any toxic effect on the kidney. This study investigate whether clonidine, methyldopa, rilmenidine, amlodipine and ramipril establish nephrotoxic effects in rats.