A COMPARATIVE INVESTIGATION OF THE NEPHROTOXIC EFFECTS OF VARIOUS ANTIHYPERTENSIVE DRUGS IN RATS: BIOCHEMICAL AND HISTOPATHOLOGICAL ANALYSIS
ACTA MEDICA MEDITERRANEA, vol.30, no.2, pp.515-521, 2014 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 30 Issue: 2
- Publication Date: 2014
- Journal Name: ACTA MEDICA MEDITERRANEA
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.515-521
- Recep Tayyip Erdoğan University Affiliated: Yes
Abstract
Aims: Hypertension is known to cause potentially fatal kidney damage. However, it is unclear whether long-term use of antihypertensive drugs establishes any toxic effect on the kidney. This study investigate whether clonidine, methyldopa, rilmenidine, amlodipine and ramipril establish nephrotoxic effects in rats.