Thiol/disulphide homeostasis in patients with rheumatoid arthritis: a potential link with disease activity and preclinical atherosclerosis

Beyazal S. M., Arpa M., Devrimsel G., Yildirim M., EREL Ö., Erdogan T.

ACTA REUMATOLOGICA PORTUGUESA, vol.46, no.1, pp.23-31, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 1
  • Publication Date: 2021
  • Journal Name: ACTA REUMATOLOGICA PORTUGUESA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals
  • Page Numbers: pp.23-31
  • Keywords: Rheumatoid arthritis, Thiol/disulphide homeostasis, Disease activity, Preclinical atherosclerosis
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

Introduction/objectives: Thiols are crucial anti-oxidant agents that contain a sulfhydryl group; they play an important role in defence against reactive oxygen species. We aimed to determine the thiol/disulphide homeostasis in rheumatoid arthritis ( RA) patients in conjunction with its association with disease activity, preclinical atherosclerosis, and other disease-related indices.