ATHEROSCLEROSIS, vol.217, no.1, pp.125-129, 2011 (Peer-Reviewed Journal)
Article / Article
Science Citation Index Expanded, Scopus
Biomarkers, Epicardial fat thickness, Coronary flow reserve, Adipokines, Nonalcoholic fatty liver disease, METABOLIC SYNDROME, SERUM-LEVELS, CHEST-PAIN, ARTERY, CHEMERIN, WOMEN, ECHOCARDIOGRAPHY, INFLAMMATION, MARKER, RISK
Background: Patients with nonalcoholic fatty liver disease (NAFLD) have a reduced coronary flow reserve (CFR) and an increased risk of cardiovascular disease. The fat cells that surround coronary arteries may play a central and underrecognized role in development of cardiovascular disease through the systemic secretion of adipokines. We therefore evaluated the relation of epicardial fat thickness, serum levels of epicardial fat-related adipokines (chemerin and vaspin), and CFR in patients with NAFLD.