DAHUDER Medical Journal, vol.1, no.1, pp.22-24, 2021 (Peer-Reviewed Journal)
Alkaptonuria is a rare autosomal recessive metabolic disease due to a deficiency of e the homogentisic acid
oxidase enzyme. We report two cases with advanced age. Our aim is to draw attention to the fact that alkaptonuria
should suggestions for clarity in every patient who shows clinical features regardless of age. We diagnosed two
patients, 61 and 69 years old, with alkaptonuria. Alkaptonuria is a rare disease that presents with multisystemic
manifestation. While early detection of the clinical signs of the disease provides early diagnosis, appropriate
treatment can significantly increase the quality of life.