Aortic propagation velocity in the prediction of coronary artery disease severity.


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Bakirci E. M. , Degirmenci H., Duman H. , Demirelli S., Hamur H., Buyuklu M., ...More

Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, vol.166, pp.51-56, 2022 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 166
  • Publication Date: 2022
  • Doi Number: 10.5507/bp.2021.001
  • Title of Journal : Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia
  • Page Numbers: pp.51-56
  • Keywords: APV, CIMT, CAD, SYNTAX score, INTIMA-MEDIA THICKNESS, SYNTAX SCORE, CARDIOVASCULAR-DISEASE, CLINICAL-OUTCOMES, ATHEROSCLEROSIS, LESIONS, RISK, INTERVENTIONS, COMPLEXITY, MARKER

Abstract

Aims. To investigate the association of the aortic propagation velocity (APV) with coronary artery disease (CAD) in patients with stable angina pectoris (SAP) through SYNTAX scores (SS). ethods. The study population comprised 214 SAP subjects who received a coronary angiography. The APV and ca-rotid intima-media thickness (CIMT) were examined and SS was calculated. Subjects were grouped following specific SS criteria: SS less than 22 (low) and SS greater than or equal to 22 (high). Results. High SS subjects had lower APV compared to low SS [39.0 (32.0-51.7) vs. 55.0 (45.0-62.0) cm/s, respectively; P<0.001] and higher CIMT (0.86 +/- 0.24 vs. 0.74 +/- 0.21 mm, respectively; P<0.001). APV demonstrated a negative cor-relation with the CIMT (r=-0.239, P<0.001), age (r=-0.188, P=0.006) , and SS (r=-0.561, P <0.001) and showed a positive association with LV ejection fraction (r=0.163, P=0.017). APV, CIMT, diabetes, low-density lipoprotein cholesterol (LDL-C), and age were determined to be markers independently of a high SS. Conclusion. APV, CIMT, diabetes, LDL-C and age are independently linked to the CAD severity of SAP subjects. Decreased APV, an indicator of subclinical atherosclerosis, may independently help determine the severity of atherosclerotic CAD in SAP patients.