Cox-2 Expression and Microvessel Density in Clear Cell Type Renal Cell Carcinoma

Gucer H., Sahan E., Igdem A. A., Tetikkurt U. S., Erdogan N.

TURKISH JOURNAL OF PATHOLOGY, vol.25, no.2, pp.13-19, 2009 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 2
  • Publication Date: 2009
  • Doi Number: 10.5146/tjpath.2009.00966
  • Journal Name: TURKISH JOURNAL OF PATHOLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.13-19
  • Keywords: Renal cell carcinoma, COX-2, Immunohistochemistry, Microvessel density
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

Objective: Overexpression of cyclooxygenase-2 (COX-2) and its association with angiogenesis have been shown in various carcinomas. In this study, we investigated COX-2 expression in clear cell type renal cell carcinoma and its association with microvessel density and various clinicopathologic parameters.