Serum macrophage migration inhibitory factor levels in Hashimoto's thyroiditis; a case control study.

Ayaz T., Baydur Şahin S., Şahin O. Z., Cumhur Cüre M., Sümer F., İlkkılıç K.

THYROID RESEARCH, vol.7, no.1, pp.11, 2014 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 1
  • Publication Date: 2014
  • Doi Number: 10.1186/s13044-014-0011-1
  • Journal Name: THYROID RESEARCH
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
  • Page Numbers: pp.11
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

Objective: The cell-mediated immune process by CD4+ and CD8+ lymphocyte subsets of T-cells has a major role in the pathogenesis of Hashimoto's thyroiditis (HT). However, the exact mechanisms of initiation and progression of thyroid autoimmunity have not been completely clarified yet. Macrophage migration inhibitory factor (MIF) is commonly recognized as playing vital roles in various autoimmune diseases. Ee aimed to investigate serum MIF levels in subjects with HT and correlate them with the level of thyroid hormones and autoantibodies.