BIOORGANIC CHEMISTRY, vol.114, 2021 (Peer-Reviewed Journal)
Article / Review
Science Citation Index Expanded, Scopus, Academic Search Premier, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, Chimica, EMBASE, MEDLINE, Veterinary Science Database
N-heterocyclic compound, Antiviral activity, Structure-activity relationship, BIOLOGICAL EVALUATION, MOLECULAR DOCKING, INDOLE-DERIVATIVES, VIRUS, INHIBITORS, MICROWAVE, ANALOGS, DESIGN, DISCOVERY, HYBRIDS
N-heterocycles are important, not only because of their abundance, but above all because of their chemical, biological and technical significance. They play an important role in biological investigation such as anticancer, antiinflammatory, antibacterial, antiviral, anti-tumor, antidiabetic, etc. In this study, we focused on examining synthesized some 5- or 6-ring N-heterocyclic compounds that showed the antiviral activity in last 5 years, and investigation of these compounds structure-activity relationship studies. This review will be useful to scientists in research fields of organic synthesis, medicinal chemistry, and pharmacology.