Recent studies of nitrogen containing heterocyclic compounds as novel antiviral agents: A review

Mermer A., KELEŞ T., Sirin Y.

BIOORGANIC CHEMISTRY, cilt.114, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 114
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1016/j.bioorg.2021.105076
  • Dergi Adı: BIOORGANIC CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, Chimica, EMBASE, MEDLINE, Veterinary Science Database
  • Anahtar Kelimeler: N-heterocyclic compound, Antiviral activity, Structure-activity relationship, BIOLOGICAL EVALUATION, MOLECULAR DOCKING, INDOLE-DERIVATIVES, VIRUS, INHIBITORS, MICROWAVE, ANALOGS, DESIGN, DISCOVERY, HYBRIDS
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

N-heterocycles are important, not only because of their abundance, but above all because of their chemical, biological and technical significance. They play an important role in biological investigation such as anticancer, antiinflammatory, antibacterial, antiviral, anti-tumor, antidiabetic, etc. In this study, we focused on examining synthesized some 5- or 6-ring N-heterocyclic compounds that showed the antiviral activity in last 5 years, and investigation of these compounds structure-activity relationship studies. This review will be useful to scientists in research fields of organic synthesis, medicinal chemistry, and pharmacology.