Serum Levels of Hepcidin in Patients with Biopsy-Proven Nonalcoholic Fatty Liver Disease

Senates E., YILMAZ Y., Colak Y., Ozturk O., Altunoz M. E., Kurt R., ...More

METABOLIC SYNDROME AND RELATED DISORDERS, vol.9, no.4, pp.287-290, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 9 Issue: 4
  • Publication Date: 2011
  • Doi Number: 10.1089/met.2010.0121
  • Journal Name: METABOLIC SYNDROME AND RELATED DISORDERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.287-290
  • Recep Tayyip Erdoğan University Affiliated: No

Abstract

Background: Research suggests the presence of mild-to-moderate iron overload in patients with nonalcoholic fatty liver disease (NAFLD). The role played by hepcidin, the master regulatory hormone of systemic iron metabolism, in the pathogenesis of NAFLD remains controversial. The aims of this study were to: (1) Evaluate serum hepcidin levels in patients with biopsy-proven NAFLD and age-and sex-matched controls and (2) identify the potential associations of hepcidin with the clinical and biochemical characteristics of the study participants.