Medicine Science, cilt.11, sa.4, ss.1654-1659, 2022 (Hakemli Dergi)
This study presents to evaluate patients with malignant or operated for benign reasons in terms of the Eastern Black Sea region of Turkey which is an endemic region of Goiter. Within the scope of the study, 460 patients over the age of 18 who applied to the RecepTayip Erdoğan University Training and Research Hospital General Surgery Outpatient Clinic between January 2013 and July 2016 and underwent total thyroidectomy or hemithyroidectomy for benign or malign reasons were retrospectively analyzed. Age, gender, TSH values of the patients, preoperative (preop.) Thyroid or neck ultrasonography (USG) reports, thyroid fine-needle aspiration biopsy (FNAB) results, and pathological/morphological examination results were evaluated. 352 of 460 patients were women (76.5%) and the mean age of all patients was calculated as 52.2 (± 11.39). 70 cases (18%) non-diagnostic cytology, 104 cases (26.8%) benign cytology, 59 cases (15.2%) atypia of uncertain significance, 61 cases (15.7%) suspicion of follicular neoplasia/neoplasia, 78 cases (20.1%) were suspected of malignancy and 16 cases (4.1%) were detected as malignant cytology. While malignancy was diagnosed histopathologically in 248 of 352 female patients who were operated on (70.5%), malignancy was detected in 81 of 108 male patients (75%). The most common thyroid papillary microcarcinoma (51.5%) was observed in histopathological examination. While tumor diameter was <1cm in 53% of patients, the multifocality was detected in 57.3%. When comparing the results of patients who underwent thyroidectomy in our city, and its surroundings where is an endemic goiter region, with the results in the literature, it showed heterogeneity, and our study was found to be above the rate of malignancy in the histopathological examination of Turkey and the world average.