The degree of premature hair graying as an independent risk marker for coronary artery disease: a predictor of biological age rather than chronological age

KOCAMAN S. A., Cetin M., DURAKOĞLUGİL M. E., ERDOĞAN T., CANGA A., ÇİÇEK Y., ...Daha Fazla

ANATOLIAN JOURNAL OF CARDIOLOGY, cilt.12, sa.6, ss.457-463, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Sayı: 6
  • Basım Tarihi: 2012
  • Doi Numarası: 10.5152/akd.2012.150
  • Dergi Adı: ANATOLIAN JOURNAL OF CARDIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CINAHL, EMBASE, MEDLINE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.457-463
  • Anahtar Kelimeler: Hair graying, cardiovascular risk factors, coronary atherosclerotic burden, biological age, chronological age, vascular aging, regression analysis, ENDOTHELIAL PROGENITOR CELLS, HEART-DISEASE, GENERAL-POPULATION, MEN, ATHEROSCLEROSIS, BALDNESS, NUMBER, BLOOD
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

Objective: Age is the most important and uncorrectable coronary risk factor at the moment. The concept of measuring aging biologically rather than only chronologically may be of importance in clinical practice. Hair graying is the most apparent sign of biological aging in humans, yet its mechanism is largely unknown. Today, it is known that cardiovascular risk factors (CVRFs), especially in combination, cause premature atherosclerosis. In our opinion, premature hair graying or whitening may represent early atherosclerotic changes as a surrogate of host response to the CVRFs. In this study, we planned to investigate the relationship of hair graying with CVRFs and coronary atherosclerotic burden in order to determine whether it is an independent marker for coronary artery disease (CAD).