A convenient method for the synthesis of 3,4-dihydroquinazolines from iminoester hydrochlorides via microwave irradiation


Karaali N.

JOURNAL OF CHEMICAL RESEARCH, cilt.43, ss.140-143, 2019 (SCI İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 43
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1177/1747519819857513
  • Dergi Adı: JOURNAL OF CHEMICAL RESEARCH
  • Sayfa Sayıları: ss.140-143

Özet

This is work presents a simple and practical strategy for the synthesis of 2-substituted-3,4-dihydroquinazolines in which the ring closure reaction of 2-aminobenzylamine with corresponding iminoester hydrochlorides via microwave irradiation allows the formation of the target compounds. Also, the 3,4-quinazoline derivatives were synthesized by conventional heating procedures for comparison in terms of reaction time and yield.