A convenient method for the synthesis of 3,4-dihydroquinazolines from iminoester hydrochlorides via microwave irradiation


Karaali N.

JOURNAL OF CHEMICAL RESEARCH, vol.43, pp.140-143, 2019 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 43
  • Publication Date: 2019
  • Doi Number: 10.1177/1747519819857513
  • Title of Journal : JOURNAL OF CHEMICAL RESEARCH
  • Page Numbers: pp.140-143

Abstract

This is work presents a simple and practical strategy for the synthesis of 2-substituted-3,4-dihydroquinazolines in which the ring closure reaction of 2-aminobenzylamine with corresponding iminoester hydrochlorides via microwave irradiation allows the formation of the target compounds. Also, the 3,4-quinazoline derivatives were synthesized by conventional heating procedures for comparison in terms of reaction time and yield.