The Protective Effect of Adalimumab on Renal Injury in a Model of Abdominal Aorta Cross-Clamping


Cure M. C., Cure E., Kalkan Y., Tumkaya L., Aydin I., Kirbas A., ...More

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, vol.25, no.2, pp.219-226, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 2
  • Publication Date: 2016
  • Doi Number: 10.17219/acem/33250
  • Journal Name: ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.219-226
  • Keywords: ischemia, reperfusion injury, adalimumab, carbonic anhydrases, tumor necrosis factor alpha, CARBONIC-ANHYDRASE-II, ISCHEMIA-REPERFUSION, ISCHEMIA/REPERFUSION INJURY, RADICAL-ANION, BICARBONATE, INFLAMMATION, EXPRESSION, INTERLEUKIN-6, PRETREATMENT, INHIBITION
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

Background. Adalimumab (ADA) is a potent inhibitor of tumor necrosis factor (TNF-alpha). ADA treatment suppresses proinflammatory cytokines, leading to a decrease or inhibition of the inflammatory process.