The Protective Effect of Adalimumab on Renal Injury in a Model of Abdominal Aorta Cross-Clamping

Cure M. C., Cure E., Kalkan Y., Tumkaya L., Aydin I., Kirbas A., ...Daha Fazla

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, cilt.25, sa.2, ss.219-226, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.17219/acem/33250
  • Dergi Adı: ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.219-226
  • Anahtar Kelimeler: ischemia, reperfusion injury, adalimumab, carbonic anhydrases, tumor necrosis factor alpha, CARBONIC-ANHYDRASE-II, ISCHEMIA-REPERFUSION, ISCHEMIA/REPERFUSION INJURY, RADICAL-ANION, BICARBONATE, INFLAMMATION, EXPRESSION, INTERLEUKIN-6, PRETREATMENT, INHIBITION
  • Recep Tayyip Erdoğan Üniversitesi Adresli: Evet

Özet

Background. Adalimumab (ADA) is a potent inhibitor of tumor necrosis factor (TNF-alpha). ADA treatment suppresses proinflammatory cytokines, leading to a decrease or inhibition of the inflammatory process.