Changes in the etiology of chronic liver disease by referral to a FibroScan center: Increasing prevalence of the nonalcoholic fatty liver disease

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Eris T., Hassan M., Hikal Y., Sawah E., Daneshgar F., Teker A. G., ...More

HEPATOLOGY FORUM, vol.4, no.1, pp.7-13, 2023 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 4 Issue: 1
  • Publication Date: 2023
  • Doi Number: 10.14744/hf.2022.2022.0042
  • Journal Name: HEPATOLOGY FORUM
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.7-13
  • Keywords: Chronic liver disease, indications, liver fibrosis, CONTROLLED ATTENUATION PARAMETER, HEPATIC STEATOSIS, STIFFNESS MEASUREMENT, TURKEY, STEATOHEPATITIS, CARE, HBV
  • Recep Tayyip Erdoğan University Affiliated: No

Abstract

Background and Aim: Chronic liver disease (CLD) is a leading cause of morbidity and mortality worldwide with a wide etiological spectrum. Fi-broScan (R) is used for follow-up of fibrosis and steatosis. This single -cen-ter study aims to review the distribution of indications by referral to Fi-broScan (R).Materials and Methods: Demographic characteristics, CLD etiolo-gies, and FibroScan (R) parameters of the patients who were referred to our tertiary care center between 2013 and 2021 were retrospectively evaluated.Results: Out of 9345 patients, 4946 (52.93%) were males, and the medi-an age was 48 [18-88] years. Nonalcoholic fatty liver disease (NAFLD) was the most common indication (N=4768, 51.02%), followed by hepa-titis B (N=3194, 34.18%) and hepatitis C (N=707, 7.57%). Adjusting for age, sex, and CLD etiology, the results revealed that patients with old-er age (Odds ratio (OR)=2.908; confidence interval (CI)=2.597-3.256; p<0.001) and patients with hepatitis C (OR=2.582; CI=2.168-3.075; p<0.001), alcoholic liver disease (OR=2.019; CI=1.524-2.674, p<0.001), and autoimmune hepatitis (OR=2.138; CI=1.360-3.660, p<0.001) had increased odds of advanced liver fibrosis compared to NAFLD.Conclusion: NAFLD was the most common indication for referral to FibroScan (R).