Liver function tests: Association with cardiovascular outcomes

Yılmaz Y.

World Journal of Hepatology, vol.2, pp.143-145, 2010 (Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 2
  • Publication Date: 2010
  • Doi Number: 10.4254/wjh.v2.i4.143
  • Journal Name: World Journal of Hepatology
  • Journal Indexes: Scopus
  • Page Numbers: pp.143-145
  • Keywords: Nonalcoholic fatty liver disease, Liver function tests, Cardiovascular disease, Outcomes
  • Recep Tayyip Erdoğan University Affiliated: No


An association between nonalcoholic fatty liver disease and cardiovascular disease has been repeatedly reported. Several studies have focused on levels of gammaglutamyltransferase (GGT) and alanine aminotransferase (ALT) in relation to cardiovascular outcomes. Evidence indicates that GGT may have a potential role for cardiovascular risk stratification while the role of ALT for cardiac prognosis remains controversial. A conceptual framework that includes not only GGT and ALT but also markers of hepatocyte apoptosis such as cytokeratin-18 fragments should be developed. (c) 2010 Baishideng. All rights reserved.