The independent relationship of epicardial adipose tissue with carotid intima-media thickness and endothelial functions: the association of pulse wave velocity with the active facilitated arterial conduction concept

KOCAMAN S. A., DURAKOĞLUGİL M. E., Cetin M., ERDOĞAN T., ERGUL E., CANGA A.

BLOOD PRESSURE MONITORING, vol.18, no.2, pp.85-93, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 2
  • Publication Date: 2013
  • Doi Number: 10.1097/mbp.0b013e32835ebbb5
  • Journal Name: BLOOD PRESSURE MONITORING
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.85-93
  • Keywords: arterial conduction, carotid intima-media thickness, endothelial dysfunction, epicardial adipose tissue, hypertension, pulse wave velocity, CORONARY FLOW RESERVE, CARDIOVASCULAR MORTALITY, DIASTOLIC DYSFUNCTION, MYOCARDIAL FIBROSIS, DEPENDENT DILATION, AORTIC STIFFNESS, RISK-FACTORS, FAT, OBESITY, HEART
  • Recep Tayyip Erdoğan University Affiliated: Yes

Abstract

Background Hypertension, identifiable by elevated blood pressure (BP), is a heterogeneous multifactorial disorder. Epicardial adipose tissue (EAT), a special fat depot that is related to visceral fat rather than total adiposity, shares the same microcirculation with myocardial tissue and coronary vessels. Recent studies have identified EAT as an active organ, which secretes several mediators, called adipokines, affecting the vascular system. The aim of this study was to evaluate the potential association between EAT and BP, endothelial function, carotid intima-media thickness (CIMT), and pulse wave velocity (PWV) independent of conventional and novel metabolic risk factors in patients with previously untreated hypertension.