Assoc. Prof. HATİCE SEVİM NALKIRAN

Metrics

Publication

Publication (WoS)

Publication (Scopus)

Citation (WoS)

166

H-Index (WoS)

Citation (Scopus)

164

H-Index (Scopus)

Citation (Scholar)

279

H-Index (Scholar)

Total Citation Count

166

Project

Thesis Advisory

Open Access

UN Sustainable Development Goals

Education

2008 - 2012

Doctorate

University Of New South Wales, Prince of Wales Clinical School, Australia

2002 - 2006

Undergraduate

Pamukkale University, Faculty Of Arts And Scıences, Department Of Bıology, Turkey

Dissertations

2012

Doctorate

Determining Biological Factors Associated with Chemotherapy Response in Glioblastoma Patients

University Of New South Wales

Foreign Languages

C1 Advanced

English

Certificates, Courses and Trainings

2008

Radiation Safety in Laboratories

Occupational Health and Safety

University of Sydney, Radiation Health Queensland

2006

Biyolojik Araştırmalarda Deneysel Hayvanların Kullanımı-IV/Training Program for Animal Use in Experimental Studies

Other

Pamukkale University, Faculty of Medicine

Academic Positions

2025 - Present

Associate Professor

Recep Tayyip Erdogan University, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü

2018 - 2025

Assistant Professor

Recep Tayyip Erdogan University, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü

2013 - 2018

Assistant Professor

Recep Tayyip Erdogan University, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü

2013 - 2013

Research Assistant

Recep Tayyip Erdogan University, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü

2012 - 2012

Research Assistant

--Seçiniz--, University Of New South Wales, Lowy Cancer Research Centre

Managerial Experience

2025 - Present

Performance Evaluation Commission Member

Recep Tayyip Erdogan University, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü

2025 - Present

Deputy Head of Department

Recep Tayyip Erdogan University, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü

2025 - Present

Head of Department

Recep Tayyip Erdogan University, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü

2025 - Present

Department Academic Incentive Evaluation Commission Member

Recep Tayyip Erdogan University, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü

2024 - Present

AR-GE ve Projeler Tıp Fakültesi Birim Komisyonu Temel Tıp Sorumlusu

Recep Tayyip Erdogan University, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü

2023 - Present

Program Accreditation-Self-Assessment Committee Member

Recep Tayyip Erdogan University, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü

2020 - Present

Department Academic Incentive Evaluation Commission Member

Recep Tayyip Erdogan University, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü

2019 - Present

Measurement and Evaluation Board Member

Recep Tayyip Erdogan University, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü

2020 - 2024

Erasmus Program Department Coordinator

Recep Tayyip Erdogan University, Tıp Fakültesi

2021 - 2022

Accreditation, Continuous Improvement, and Renewal Board Member

Recep Tayyip Erdogan University, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü

2021 - 2022

Program Accreditation-Self-Assessment Committee Member

Recep Tayyip Erdogan University, Tıp Fakültesi

2013 - 2022

Ethics Committee Member

Recep Tayyip Erdogan University, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü

2016 - 2017

Program Coordinator

Recep Tayyip Erdogan University, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü

2015 - 2016

Assistant Director of the Institute

Recep Tayyip Erdogan University, Tıp Fakültesi, Sağlık Bilimleri Enstitüsü

Courses

Postgraduate

The Molecular Biology of Cancer

Undergraduate

Medical Biology and Genetics

Associate Degree

Methods in Molecular Biology

Medical Biology and Genetics

Supervised Theses

2023

Postgraduate

Mesane kanseri hastalarında CDC20 ve siklin B1 gen ekspresyon seviyelerinin incelenmesi

Sevim Nalkıran H. (Advisor)

İ.BİRİ(Student)

2021

Postgraduate

Investigation of the Prognostic Importance of Expressions of PD-1 and PD-L1 in Bladder Cancer Patients

Sevim Nalkıran H. (Advisor)

S.DURUR(Student)

Articles

2026

1. Lavandula stoechas Ethanol Extracts Induce Apoptosis in Breast, Bladder, and Glioblastoma Cancer Cells

Nalkıran İ., Nalkiran H.

PHARMACEUTICS , vol.18, no.4, pp.1-19, 2026 (SCI-Expanded, Scopus)

2026

2. Electrochemically optimized multi-component polyacrylonitrile nanofiber scaffolds as a platform for three-dimensional glioblastoma cell culture

Kurt S., BAL ALTUNTAŞ D., SEVİM NALKIRAN H., Aslan S., Kocak C., Mamuk A. E., et al.

SCIENTIFIC REPORTS , vol.16, no.1, 2026 (SCI-Expanded, Scopus)

2026

3. Three-dimensional cytosensor for glioblastoma cell analysis using coumarin-integrated nanofiber scaffolds on ITO electrodes

Kurt Ş., Bal Altuntaş D., Sevim Nalkıran H., Aslan S., Mamuk A. E., Koçak Ç., et al.

SENSORS AND ACTUATORS, B: CHEMICAL , vol.449, no.139006, pp.1, 2026 (SCI-Expanded, Scopus)

2026

4. Epigenetic and mitoepigenetic regulation in cancer and therapeutic perspectives

Celik-Uzuner S., NALKIRAN İ., UZUNER U., SEVİM NALKIRAN H.

Frontiers in Pharmacology , vol.17, 2026 (SCI-Expanded, Scopus)

2025

5. Integrative Machine Learning Model for Overall Survival Prediction in Breast Cancer Using Clinical and Transcriptomic Data

Kıvrak M., Nalkiran H. S., Kesen O., Nalkiran I.

Biology , vol.14, no.11, 2025 (SCI-Expanded, Scopus)

2025

6. Anticancer Effects and Phytochemical Profile of Lavandula stoechas

Sevim Nalkıran H., Nalkıran İ.

PHARMACEUTICALS , vol.18, pp.1-16, 2025 (SCI-Expanded, Scopus)

2025

7. Investigation of the Effect of Krill Oil on Sortilin in Liver and Adipose Tissue in Obese Rats

ATAK M., Sahin A. B., YILMAZ KUTLU E., KILIÇ H., Uydu H. A., SEVİM NALKIRAN H., et al.

MOLECULAR NUTRITION & FOOD RESEARCH , vol.69, no.22, 2025 (SCI-Expanded, Scopus)

2025

8. Modulation of PD-L1 Expression by Cisplatin and Gemcitabine in Bladder Cancer Cells

Nalkıran İ., Sevim Nalkıran H.

Celal Bayar Üniversitesi Fen Bilimleri Dergisi , vol.21, no.3, pp.28-34, 2025 (TRDizin)

2025

9. Exploring the anticancer potential of resveratrol through in silico interaction analysis with mitotic regulators Aurora A, Aurora B, and BubR1

Nalkıran İ., Sevim Nalkıran H.

Medicine Science , vol.14, no.3, pp.765-770, 2025 (TRDizin)

2025

10. Metformin as a modulator of mitochondria-mediated antiviral innate immunity: Insights from molecular docking analysis

Nalkiran I., Sevim Nalkiran H.

Medicine Science , vol.14, no.2, pp.472-481, 2025 (TRDizin)

2025

11. In Silico Identification of LSD1 Inhibition-Responsive Targets in Small Cell Lung Cancer.

Nalkiran İ., Sevim Nalkiran H., Ozcelik N., Kivrak M.

Bioengineering (Basel, Switzerland) , vol.12, no.5, 2025 (SCI-Expanded, Scopus)

2025

12. Repurposing ProTAME for Bladder Cancer: A Combined Therapeutic Approach Targeting Cell Migration and MMP Regulation

Nalkiran İ., Sevim Nalkıran H.

BIOLOGY-BASEL , vol.14, no.3, pp.1-21, 2025 (SCI-Expanded, Scopus)

2025

13. Exploring the Therapeutic Potential of the DOT1L Inhibitor EPZ004777 Using Bioinformatics and Molecular Docking Approaches in Acute Myeloid Leukemia

Kivrak M., Nalkiran İ., Sevim Nalkiran H.

CURRENT ISSUES IN MOLECULAR BIOLOGY , vol.47, no.3, pp.1-23, 2025 (SCI-Expanded, Scopus)

2025

14. **Phytochemical Profile and Anticancer Potential of Helichrysum arenarium Extracts on Glioblastoma, Bladder Cancer, and Breast Cancer Cells**

Nalkiran İ., Sevim Nalkiran H.

PHARMACEUTICALS , vol.18, no.2, pp.1-18, 2025 (SCI-Expanded, Scopus)

2025

15. Identification and Characterization of a Novel Rat MAVS Variant Modulating NFκB Signaling

NALKIRAN İ., SEVİM NALKIRAN H.

BIOMOLECULES , vol.15, no.1, 2025 (SCI-Expanded, Scopus)

2025

16. CDC20 and CCNB1 Overexpression as Prognostic Markers in Bladder Cancer

Sevim Nalkiran H., Biri I., Nalkıran İ., Uzun H., Durur S., Bedir R.

DIAGNOSTICS , vol.15, no.1, 2025 (SCI-Expanded, Scopus)

2024

17. An Electrochemical Immuno-cytosensor Modified with Nanofibers for the Determination of a Carcinoembryonic Antigen

Yildizbakan Z., Altuntaş D., SEVİM NALKIRAN H., Aslan S., Mamuk A. E., Koçak Ç., et al.

BIOCHIP JOURNAL , vol.18, no.3, pp.464-476, 2024 (SCI-Expanded, Scopus)

2024

18. Effects of Melaleuca alternifolia (Tea Tree) Oil and Vitamin E Combination on the Viability of Non-Small Cell Lung Cancer Cells

Nalkıran İ., Sevim Nalkıran H.

Rize Medical Journal , vol.1, no.2, pp.34-48, 2024 (Peer-Reviewed Journal)

2024

19. Inhibition of O6-methylguanine-DNA-methyltransferase (MGMT) by lomeguatrib reduces multiple myeloma cell viability and impairs DNA repair in MGMT-proficient cells

Akcora-Yildiz D., ÖZKAN T., Cetintav B., Yukselten Y., Calis S., Sevim-Nalkiran H., et al.

CHEMICAL BIOLOGY & DRUG DESIGN , vol.103, no.2, 2024 (SCI-Expanded, Scopus)

2024

20. The association of Sort1 expression with LDL subfraction and inflammation in patients with coronary artery disease

Atak M., Sevim Nalkiran H., Bostan M., Uydu H. A.

Acta Cardiologica , vol.79, no.2, pp.159-166, 2024 (SCI-Expanded, Scopus)

2023

21. To Determine LDL Phenotypes Using Lipids, Lipoproteins, Apoproteins, and sdLDL Through Association Rule Mining

Atak M., Kıvrak M., Sevim Nalkıran H., Uydu H. A., Şatıroğlu Ö.

Journal of clinical practice and research , vol.45, no.6, pp.632-639, 2023 (ESCI, TRDizin)

2023

22. Targeting the anaphase-promoting complex/cyclosome (APC/C) enhanced antiproliferative and apoptotic response in bladder cancer

Sevim Nalkiran H., Akcora Yildiz D., Saydam F., Guzel A. I., Nalkiran İ.

Saudi Journal of Biological Sciences , vol.30, no.3, 2023 (SCI-Expanded, Scopus)

2023

23. Genetic variations in OLR1 gene associated with PCOS and atherosclerotic risk factors.

Sahin S. B., Nalkiran İ., Ayaz T., Irfan Guzel A., Eldes T., Calapoglu T., et al.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research , vol.71, no.2, pp.113-123, 2023 (SCI-Expanded, Scopus)

2023

24. Investigation of a Glioblastoma Risk-Associated SNP of the PTPRB Gene in Familial Glioblastoma

Sevim Nalkıran H., Rakıcı S., Nalkıran İ.

Journal of oncological sciences , vol.9, no.1, pp.15-22, 2023 (Scopus, TRDizin)

2023

25. Prognostic importance of PD-L1 expression in bladder cancer patients.

Durur S., Uzun H., Bedir R., Nalkiran İ., Nalkiran H. S.

Journal of cancer research and therapeutics , vol.19, no.Suppl 2, 2023 (SCI-Expanded, Scopus)

2022

26. Development of MoS2 and Au nanoparticle including disposable CEA-based immuno-cytosensor platforms

BAL ALTUNTAŞ D., SEVİM NALKIRAN H., ASLAN S., YOLCU Z.

CHEMICAL PAPERS , vol.76, no.8, pp.5217-5229, 2022 (SCI-Expanded, Scopus)

2021

27. Anticancer effects of a novel herbal combination as a potential therapeutic candidate against lung cancer

SAYDAM F., Nalkiran H.

EUROPEAN JOURNAL OF INTEGRATIVE MEDICINE , vol.48, 2021 (SCI-Expanded, Scopus)

2021

28. Comparison of DNA isolation methods from mammalian sperm cells and development of a new protocol

SEVİM NALKIRAN H., NALKIRAN İ., RAKICI S., TÜMKAYA L., GÜZEL A. İ.

Medicine Science , vol.10, no.2, pp.440-443, 2021 (TRDizin)

2020

29. Pelvic Radiation-Induced Testicular Damage: An Experimental Study at 1 Gray.

RAKICI S., Guzel A. İ., TUMKAYA L., Nalkiran H. S., MERCANTEPE T.

Systems biology in reproductive medicine , vol.66, no.2, pp.89-98, 2020 (SCI-Expanded, Scopus)

2019

30. Association of paraoxonase-1 L55M and Q192R polymorphisms with PCOS risk and potential risk factors for atherosclerosis

Nalkiran H., Sahin S. B., Ayaz T., Nalkiran I., Guzel A. I., Eldes T., et al.

BIOMARKERS IN MEDICINE , vol.13, no.4, pp.279-289, 2019 (SCI-Expanded, Scopus)

2019

31. Ibudilast sensitizes glioblastoma to temozolomide by targeting Macrophage Migration Inhibitory Factor (MIF)

Ha W., Sevim-Nalkiran H., ZAMAN A. M., MATSUDA K., Khasraw M., NOWAK A. K., et al.

SCIENTIFIC REPORTS , vol.9, 2019 (SCI-Expanded, Scopus)

2018

32. Effects of Hippophae rhamnoides extract on oxidative mucosal injuryinduced by cisplatin in rat jejunum.

Arslan A., ÖZÇİÇEK F., KESKİN ÇİMEN F., SEVİM H., GÜLABOĞLU M., ÇETİN N., et al.

Biomedical Research-India , vol.29, no.2, pp.401-407, 2018 (Peer-Reviewed Journal)

2017

33. Is neuroglial antigen 2 a potential contributor to cilengitide response in glioblastoma?

Nalkiran H., MCDONALD K. L.

JOURNAL OF CANCER RESEARCH AND THERAPEUTICS , vol.13, no.2, pp.329-336, 2017 (SCI-Expanded, Scopus)

2016

34. Effects of nimesulide on the small intestine mucositis induced by methotrexate in rats

ARSLAN A., ÖZÇİÇEK A., SÜLEYMAN B., ÇOBAN T. A., CIMEN F. K., Nalkiran H., et al.

EXPERIMENTAL ANIMALS , vol.65, no.4, pp.329-336, 2016 (SCI-Expanded, Scopus)

2016

35. Investigation of mucus obtained from different fish species on the acute pain induced with scalpel incision in paw of rats

Cetin N., SULEYMAN B., KUYRUKLUYILDIZ U., Nalkiran H., KIRAN A., GENCOGLU S., et al.

EXPERIMENTAL ANIMALS , vol.65, no.1, pp.77-85, 2016 (SCI-Expanded, Scopus)

2016

36. Effects of Nimesulide on Oxidative Mucosal Injury Induced by Cisplatin in Rat Duodenum and Jejunum

ÖZÇİÇEK F., ÇANKAYA M., CIMEN F. K., Kafa A. H. T., Nalkiran H., SÜLEYMAN B., et al.

LATIN AMERICAN JOURNAL OF PHARMACY , vol.35, pp.1110-1115, 2016 (SCI-Expanded, Scopus)

2011

37. Etoposide-mediated glioblastoma cell death: dependent or independent on the expression of its target, topoisomerase II alpha?

Sevim H., Parkinson J. F., McDonald K. L.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY , vol.137, no.11, pp.1705-1712, 2011 (SCI-Expanded, Scopus)

2008

38. In vivo effects of Urtica urens (dwarf nettle) on the expression of CYP1A in control and 3-methylcholanthrene-exposed rats

Ozkarsli M., Sevim H., ŞEN A.

XENOBIOTICA , vol.38, no.1, pp.48-61, 2008 (SCI-Expanded, Scopus)

2007

39. ?Prevention of Carbon Tetrachloride-Induced Hepatotoxicity by Urtica urens in Rats.

Sen A., Şahin B., Agus H. H., Bayav M., SEVİM NALKIRAN H., Semiz A.

JOURNAL OF APPLIED BIOLOGICAL SCIENCES , vol.1, no.3, pp.29-32, 2007 (TRDizin)

Papers Presented at Peer-Reviewed Scientific Conferences

2024

1. Development of Electrochemical Cytosensor Using LN-18 Cells on Fibronectin Coated Electrospun PAN Nanofibers on ITO Surface

Kurt Ş., Bal Altuntaş D., Sevim Nalkıran H., Aslan S., Koçak Ç., Mamuk A. E., et al.

18th Nanoscience and Nanotechnology Conference, İstanbul, Turkey, 26 August - 28 October 2024, pp.92, (Summary Text)

2024

2. Development Of Electrochemical Cytosensor Using U-87 MG Cells On Collagen IV-Coated Electrospun PAN Nanofibers on ITO Surface Şeymanur Kurt, Tuğçe Doğru, Derya Bal Altuntaş, Hatice Sevim Nalkiran, Çağdaş Koçak, Sema Aslan, Atilla Eren Mamuk, İhsan Nalkiran

Kurt Ş., BAL ALTUNTAŞ D., SEVİM NALKIRAN H., ASLAN S., KOÇAK Ç., MAMUK A. E., et al.

18th International Nanoscience and Nanotechnology Conference, İstanbul, Turkey, 26 August 2024, (Summary Text)

2024

3. Development Of Electrochemical Cytosensor Using U-87 MG Cells on Collagen IV-Coated Electrospun PAN Nanofibers on ITO Surface

Kurt Ş., Doğru T., Bal Altuntaş D., Sevim Nalkıran H., Koçak Ç., Aslan S., et al.

18th Nanoscience and Nanotechnology Conference, İstanbul, Turkey, 26 - 28 August 2024, pp.120, (Summary Text)

2022

4. Electrochemical Biosensor for Determination of Carcinoembryonic Antigen BiomarkerUsing Human Breast Ductal Adenocarcinoma, Human Ovarian Adenocarcinoma Cancer Cells

Yıldızbakan Z., Bal Altuntaş D., Sevim Nalkıran H., Aslan S., Yolcu Z.

16th Nanoscience and Nanotechnology Conference, TÜRKİYE, 2022, Ankara, Turkey, 05 October 2022, (Summary Text)

2022

5. An Electrochemical Immunosensor Modified with Nanofibers for the Determination of a Carcinoembryonic Antigen

YILDIZBAKAN Z., BAL ALTUNTAŞ D., SEVİM NALKIRAN H., MAMUK A. E., KOÇAK Ç., ÜNLÜ C. G., et al.

16th Nanoscience and Nanotechnology Conference, Ankara, Turkey, 05 September 2022, (Summary Text)

2021

6. Anticancer properties of a new herbal combination as a potential lung cancer treatment candidate

SAYDAM F., SEVİM NALKIRAN H.

4th International Conference on Natural Products for Cancer Prevention and Therapy, Kayseri, Turkey, 18 December 2021, (Summary Text)

2021

7. Investigation of PD-L1 Gene Expression in Bladder Cancer Tissues

Durur S., Uzun H., Bedir R., Nalkıran İ., Sevim Nalkıran H.

8th Multidisciplinary Cancer Research Congress, 16 - 17 January 2021, pp.102, (Summary Text)

2020

8. Cytotoxic Effects of Melaleuca alternifolia (Tea Tree) Oil on A549 Non-Small Cell Lung Cancer and ARPE-19 Normal Epithelial Cells

SEVİM NALKIRAN H.

5th International Hippocrates Congress on Medical and Health Sciences, Online, Turkey, 19 December 2020, (Summary Text)

2019

9. Prognostic role of PD-L1 expression in anti-PD-1/PD-L1 immunotherapy for bladder cancer patients, a meta-analysis

Sevim Nalkıran H.

Eurasian Congress on Molecular Biotechnology, Trabzon, Turkey, 19 - 21 September 2019, pp.17, (Summary Text)

2017

10. Polikistik Over Sendromu Tanısı Almış Hastalarda Paraoksonaz 1 Genindeki Leu55Met ve Gln192Arg Polimorfizmlerinin Ateroskleroz riskiyle ilişkisinin Araştırılması

SEVİM NALKIRAN H., AYAZ T., NALKIRAN İ., GÜZEL A. İ., ELDEŞ T., YILDIZ Y.

2. Ege Endokrin Hastalıklar ve Genetik Sempozyumu, Turkey, 23 - 25 February 2017, (Summary Text)

2017

11. Y CHROMOSOME MICRODELTIONS IN 102 CASES: IS THE INCIDENCE OF ACQUIRED NON-OBSTRUCTIVE AZOOSPERMIA INCREASING?

UZUN H., SEVİM NALKIRAN H., AKÇA N., EREN H., NALKIRAN İ., SAYDAM F., et al.

ESAU Meeting Bodrum Turkey, Muğla, Turkey, 21 May 2017, pp.84, (Summary Text)

2017

12. Y Chromosome Microdeletions in 102 cases: Is the Incidence of Acquired Non-obstructıve Azoospermia Increasing?

UZUN H., SEVİM NALKIRAN H., AKÇA N., EREN H., NALKIRAN İ., SAYDAM F., et al.

ESAU Meeting, Muğla, Turkey, 21 May 2017, (Summary Text)

2017

13. Effect of treating glioblastoma with a cytokine inhibitor, ibudilast, in combination with temozolomide on survival in a patient-derived xenograft model.

McDonald K. L., Ha W., Sevim H., Matsuda K., Khasraw M.

53rd Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Illinois, United States Of America, 2 - 06 June 2017, vol.35, (Summary Text)

2017

14. EFFECT OF SORTILIN GEN EXPRESSION ON LDL SUBFRACTIONS AND SEVERITY OF CORONARY ARTERY DISEASE

UYDU H. A., ATAK M., BOSTAN M., SEVİM NALKIRAN H., MALKOÇ M., PINARBAŞ E., et al.

85th Congress of the European Atherosclerosis Society, Brisbane, Australia, 23 - 26 April 2017, vol.11, no.263, pp.0-104, (Summary Text)

2017

15. Simultane Familyal Glioblastom: İki Kardeş Glioblastom Vakası

RAKICI S., SEVİM NALKIRAN H., ÇETİN B., BEDİR R.

22. ULUSAL KANSER KONGRESİ, Antalya, Turkey, 19 - 23 April 2017, pp.153, (Full Text)

2017

16. Investigation of Association Between Paraoxonase-1 L55M (RS854560) and Q192R (RS662) Polymorphisms and Potential Atherosclerotic Risk Factors in PCOS Patients Patients (Polikistik Over Sendromu Tanısı Almış Hastalarda Paraoksonaz 1 Genindeki Leu55Met ve Gln192Arg Polimorfizmlerinin Ateroskleroz riskiyle ilişkisinin Araştırılması)

SEVİM NALKIRAN H., AYAZ T., NALKIRAN İ., GÜZEL A. İ., DURAKOĞLUGİL T., YILDIZ Y.

2. Ege Endokrin Hastalıklar ve Genetik Sempozyumu, İzmir, Turkey, 23 - 25 February 2017, vol.9, pp.27, (Summary Text)

2016

17. Repurposing Ibudilast in combination with temozolomide for glioblastoma

McDonald K., Ha W., SEVİM NALKIRAN H., Khasraw M.

21st Annual Scientific Meeting and Education Day of the Society for Neuro-Oncology, Scottsdale, Arizona, Arizona, United States Of America, 17 - 20 November 2016, vol.18, (Summary Text)

2016

18. Repurposing Ibudilast in combination with temozolomide for glioblastoma

McDonald K., Ha W., SEVİM NALKIRAN H., Chung L., Baxter R., Khasraw M.

13th Asian Society for Neuro-Oncology (ASNO) Meeting/9th COGNO Annual Scientific Meeting, Sydney, Australia, 11 - 14 September 2016, pp.67, (Summary Text)

2014

19. MIF/CD74 guided therapeutic strategy for relapsed glioblastoma patients

Mcdonald K. L., SEVİM NALKIRAN H., Ha W., Chung L., Baxter R.

105th Annual Meeting of the American-Association-for-Cancer-Research (AACR), California, United States Of America, 5 - 09 April 2014, vol.74, (Summary Text)

2014

20. MIF-CD74 GUIDED THERAPEUTIC STRATEGY FOR THE UPFRONT TREATMENT OF GBM PATIENTS WITH AN UNMETHYLATED MGMT PROMOTER

McDonald K. L., Ha W., Sevim H.

20th International Conference on Brain Tumor Research and Therapy, California, United States Of America, 20 - 22 July 2014, vol.16, (Summary Text)

2013

21. Improved Responsiveness to Temozolomide by Blocking MIF Expression in Glioblastoma

McDonald K. L., SEVİM NALKIRAN H.

Worldwide Innovative Networking in Personalized Cancer Medicine WIN 2013 Symposium-Personal Cancer Medicine: From Innovation to implementation, Paris, France, 10 - 12 July 2013, pp.7, (Full Text)

2012

22. Aberrant expression of low molecular weight proteins associated with response to conventional concurrent chemoradiotherapy treatment and overall survival?

SEVİM NALKIRAN H., Chung L., Wheeler H. R., Baxter R. C., McDonald K. L.

European Association of Neuro-oncology (EANO) 10th meeting, Marsilya, France, 6 - 07 September 2012, no.14, (Summary Text)

2011

23. Aberrant expression of Low-molecular-weight proteins associated with response to conventional concurrent chemoradiotherapy treatment

SEVİM NALKIRAN H., Chung L., Wheeler H. R., Baxter R. C., McDonald K. L.

16th Annual Scientific Meeting & Education Day of the Society for Neuro-Oncology, Garden Grove, United States Of America, 17 - 20 November 2011, vol.13, (Full Text)

2011

24. Protein biomarker discovery in glioblastoma using SELDI-TOF-MS

SEVİM NALKIRAN H., Chung L., Wheeler H. R., Baxter R. C., McDonald K. L.

102nd Annual Meeting of the American Association for Cancer Research, Orlando, United States Of America, 2 - 06 April 2011, vol.71, no.5094, pp.71, (Full Text)

2010

25. ?Determining Biological Factors Associated with chemotherapy response in Glioblastoma Patients

SEVİM NALKIRAN H., Maleki S., Messina M., Robinson B. G., McDonald K. L.

22nd Lorne Cancer Conference, Lorne-Melbourne, Australia, 11 - 13 February 2010, pp.24, (Full Text)

2009

26. Determining Biological Factors Associated with chemotherapy response in Glioblastoma Patients?

SEVİM NALKIRAN H., Maleki S., Messina M., Robinson B. G., McDonald K. L.

XXVIth Annual Scientific Research Meeting, Sydney, Australia, 25 November 2009, pp.51, (Full Text)

2006

27. In vivo effects of Urtica urens seed extracts on the cytochrome P450-dependent monooxygenases in the liver, lung and kidney of control and 3-methylcholanthrene-exposed rats

SEN A., Agus H. H., Bayav M., SEVİM NALKIRAN H.

14th North American ISSX Meeting, Puerto Rico, United States Of America, 22 - 26 October 2006, vol.38, pp.55-56, (Full Text)

2006

28. Karaciğer Koruyucu Urtica urens: Sıçanlarda Karbontetraklorür?ün Neden Olduğu Karaciğer Toksisitesinin U. urens ile Giderilmesi

Sen A., Şahin B., Bayav M., Agus H. H., SEVİM NALKIRAN H., Semiz A.

18. Ulusal Biyoloji Kongresi, Aydın, Turkey, 26 - 30 June 2006, no.154, pp.59, (Full Text)

2006

29. In vivo assessment of Urtica urens supplementation on rat xenobiotic metabolizing enzymes

Sen A., Agus H. H., Bayav M., SEVİM NALKIRAN H.

Federation of European Biochemical Societies, İstanbul, Turkey, 25 - 29 June 2006, vol.273, pp.300, (Full Text)

Books

2021

1. Otizm Spektrum Bozuklukları ve Sinema Terapi

SEVİM NALKIRAN H.

in: TIP ve SANAT, Doç. Dr. Sema Yılmaz Rakıcı, Editor, Akademisyen Kitabevi, Ankara, pp.83-106, 2021

Funded Projects

2026 - Present

Spexinin İndometazin ile İndüklenen Gastrik Ülser Modelinde Gastroprotektif Etkisinin Araştırılması

Project Supported by Higher Education Institutions , BAP Research Project

KARACA A. (Executive), NALKIRAN İ., SEVİM NALKIRAN H., TOKTAY E., TOPÇU A., ATAK M.

2026 - Present

Yaşa Bağlı Maküler Dejenerasyon Hastalarında HIF1a ile İlişkili Moleküler Mekanizmaların Araştırılması

Project Supported by Higher Education Institutions , BAP Research Project

SÜMER F. (Executive), SEVİM NALKIRAN H., NALKIRAN İ., Can E., KIVRAK M.

2025 - Present

Cisplatin ile Oluşturulan Testiküler Toksisite Modelinde Methylsulfonylmethanein'in (MSM)Terapötik Etkilerinin Değerlendirilmesi

Project Supported by Higher Education Institutions , BAP Research Project

(Project Abstract)

İSMAİLOĞLU P. (Executive), DENİZ E., MATARACI KARAKAŞ S., YILMAZ A., SEVİM NALKIRAN H., NALKIRAN İ., et al.

2025 - Present

Helichrysum arenarium Ekstraktının Farklı Kanser Hücre Hatlarında Apoptoz ile İlişkili Etkisinin İncelenmesi

Project Supported by Higher Education Institutions , BAP Research Project

NALKIRAN İ. (Executive), SEVİM NALKIRAN H.

2025 - Present

Tannik Asidin Glioblastoma Sferoidlerinde Sitotoksik Apoptotik ve Ferroptotik Etkilerinin İncelenmesi

Project Supported by Higher Education Institutions , BAP Research Project

SEVİM NALKIRAN H. (Executive), NALKIRAN İ., Can E.

2025 - Present

Çeşitli Anti-glokom İlaçların Lens Epitel Hücrelerinin Epitelyal-Mezenkimal Geçişi ve Migrasyonu Üzerindeki Etkileri

Project Supported by Higher Education Institutions , BAP Research Project

UZUN F. (Executive), SEVİM NALKIRAN H., NALKIRAN İ., SÜMER F.

2024 - 2027

Investigation of the Therapeutic Target Potential of Mitochondrial Proteases in Pleural Mesothelioma

TUBITAK Project , 1001 - Program for Supporting Scientific and Technological Research Projects

İrtegün Kandemir S.(Executive), Özşener Özekinci S., Onat S., Sevim Nalkıran H., Akçora Yıldız D., Oruç Z., et al.

2025 - 2025

Lavandula stoechasın Kanser Hücrelerinin İnvazyonunu İnhibe Edici Etkilerinin İncelenmesi

Project Supported by Higher Education Institutions , BAP Other

NALKIRAN İ. (Executive), SEVİM NALKIRAN H.

2022 - 2025

Development of a New 3D Glioblastoma Tumor-Microenvironment Interaction Model and the Establishment of Electrochemical Platforms

TUBITAK Project , 1001 - Program for Supporting Scientific and Technological Research Projects

Bal Altuntaş D. (Executive), Kara Subaşat H., Sevim Nalkıran H., Nalkıran İ., Aslan S., Mamuk A. E., et al.

2020 - 2024

Investigation of Targeting the MAVS Signaling Pathway as a Potential Cancer Immunotherapy Approach

TUBITAK Project , 3501 - National Young Researcher Career Development Program

Sevim Nalkıran H. (Executive), Nalkıran İ.

2020 - 2023

Lavandula stoechas esansiyel yağ ve özütünün kanser hücreleri üzerinde potansiyel sitotoksik ve anti-metastatik etkilerinin araştırılması

Project Supported by Higher Education Institutions , BAP Research Project

(Project Abstract)

SEVİM NALKIRAN H. (Executive), NALKIRAN İ.

2020 - 2021

Mesane Kanseri Hastalarında PD1 ve PDL1 Ekspresyonlarının Prognostik Öneminin İncelenmesi

Project Supported by Higher Education Institutions , BAP MSc

SEVİM NALKIRAN H. (Executive), Durur S.

2017 - 2020

Mesane kanseri hücrelerinin standart kemoterapi rejimi ve inhibitör içeren kombine terapiye karşı cevabının araştırılması

Project Supported by Higher Education Institutions , BAP Research Project

SEVİM NALKIRAN H. (Executive), NALKIRAN İ., SAYDAM F., GÜZEL A. İ.

2014 - 2018

Koroner Arter Hastalarında Sortilin Gen Bölgesiyle İlişkili Non-coding rs599839 Gen Polimorfizimin Lipoprotein Alt Fraksiyonlar İle Olan İlişkisinin İncelenmesi

Project Supported by Higher Education Institutions , BAP Research Project

UYDU H. A. (Executive), PINARBAŞ E., AKYILDIZ K., ATAK M., SEVİM NALKIRAN H., HÜNER M.

2014 - 2017

Düşük doz radyasyonun germ hücrelerinde oluşturduğu genetik ve histopatolojik değişiklikler.

Project Supported by Higher Education Institutions , BAP Research Project

RAKICI S. (Executive), TÜMKAYA L., GÜZEL A. İ., SEVİM NALKIRAN H.

2013 - 2017

Polikistik over sendromu tanısı almış hastalarda paraoksonaz 1 genindeki Leu55Met ve Gln192Arg polimorfizmlerinin ateroskleroz riskiyle ilişkisinin araştırılması

Project Supported by Higher Education Institutions , BAP Research Project

SEVİM NALKIRAN H. (Executive), NALKIRAN İ., AYAZ T., GÜZEL A. İ.

Memberships and Roles in Scientific Organizations

2022 - Present

European Association for Cancer Research

Member

2022 - Present

Moleküler Kanser Araştırma Derneği

Member

2013 - Present

Tıbbi Biyoloji ve Genetik Derneği

Member

2011 - 2020

American Association for Cancer Research

Member

2013 - 2018

European Association for Cancer Research

Member

Peer Reviews in Scientific Publications

June 2025

Medicine Science

National Scientific Refreed Journal

March 2025

MEDICAL ONCOLOGY

SCI Journal

July 2024

CHEMICAL BIOLOGY AND DRUG DESIGN

SCI Journal

July 2024

HELIYON

National Scientific Refreed Journal

September 2016

Oncotargets and therapy

SCI Journal

February 2016

Journal of Obstetrics and Gynaecology Research

SCI Journal

October 2014

Oncotargets and therapy

SCI Journal

July 2014

Oncotargets and therapy

SCI Journal

March 2014

Oncotargets and therapy

SCI Journal

November 2013

Pharmacogenomics and Personalized Medicine

Other Indexed Journal

October 2013

Oncotargets and therapy

SCI Journal

March 2013

Oncotargets and therapy

SCI Journal

Scientific Project Refereeing

October 2024

Project Supported by Higher Education Institutions

BAP Research Project, Istanbul University, Turkey

September 2024

Project Supported by Higher Education Institutions

BAP Research Project, Kütahya Health Sciences University, Turkey

January 2024

TUBITAK Project

1002 - Quick Support Program, Abdullah Gul University, Turkey

Congress and Symposium Activities

19 September 2019 - 21 September 2020

Eurasian Congress on Molecular Biotechnology

Invited Speaker

Trabzon-Turkey

01 March 2012 - 01 March 2012

Clinical Oncological Society of Australia (COSA) Neuro-Oncology Clinical Professional Day

Attendee

Sydney-Australia

01 November 2011 - 01 November 2011

The 16th Annual Scientific Meeting of the Society for Neuro-Oncology in Colloboration with the AANS/CMS Section on Tumors (MCOS 1002)

Attendee

California-United States Of America

Scholarships

2006 - 2012

1416 Sayılı Kanun Uyarınca Yurtdışında Lisansüstü Öğrenim Bursu

Ministry of Education

2011 - 2011

Round 1, Prince of Wales Clinical School (POWCS)

University

2011 - 2011

Round 1, Postgraduate Research Support Scheme (PRSS)

University

Citations

Total Citations (WOS): 166

h-index (WOS): 7

Jury Memberships

September-2024

September 2024

Post Graduate

- Karadeniz Teknik Üniversitesi

May-2024

May 2024

Post Graduate

Master's Thesis Defense - Karadeniz Teknik Üniversitesi

January-2024

January 2024

Post Graduate

Master's Thesis Defense - Tokat Gaziosmanpaşa Üniversitesi

September-2023

September 2023

Doctorate

Ph.D. Thesis Defense - Recep Tayyip Erdoğan Üniversitesi

August-2023

August 2023

Post Graduate

Master's Thesis Defense - Recep Tayyip Erdoğan Üniversitesi

July-2022

July 2022

Post Graduate

Master's Thesis Defense - Alanya Alaaddin Keykubat Üniversitesi

April-2020

April 2020